at least according to charles oakley
The binding location for the biotin carboxyl carrier protein domain demonstrates that tethered biotin cannot bind in the biotin carboxylase domain active site in the same orientation as free biotin, helping to explain the difference in catalysis observed between tethered biotin and free biotin substrates in biotin carboxylase enzymes. Electron density located in the biotin carboxylase domain active site is assigned to phosphonoacetate, offering a probable location for the putative carboxyphosphate intermediate formed during biotin carboxylation. The insights gained from the T882A Rhizobium etli PC crystal structure provide a new series of catalytic snapshots in PC and offer a revised perspective on catalysis in the biotin dependent enzyme family..
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He was preparing for another turn piloting America’s top sled in the Olympics when he died in his sleep in May. He was just 37, and his death sent shock waves across the close knit bobsled world. He was found with sleeping pills and alcohol in his system in what family and friends believe was an accidental yet fatal mix..
BAD NEWS FOR THE KNICKS IF: The aged Mark Jackson, who is averaging 7.7 ppg, 8.0 apg. And 3.7 rpg., starts to exhibit more of the inconsistent play that plagued him at the end of the season. If that happens, Charlie Ward will become a starter and New York will miss the spark Ward brought off the bench..
N Ley departure leaves a huge void. While critics of ESPN journalism are petty and wrong, nobody at the network compares to him in that capacity. The Lines was clearly his show. Johnson has been extremely careful with that knee, using a form of magnetic therapy over the last few weeks. The Knicks already have had one serious injury this year, losing Latrell Sprewell for 3 6 weeks with a stress fracture of the right heel. Sprewell is making good progress, according to one Knick official..
Muir was an energetic worker and a wise and cautious counsellor. Very few men in this section of country were as well read in municipal law or whose opinion was worth more. Besides this he had the genial nature that made a social companion and the sterling worth that made him a true friend.